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What causes gallstones?

Types of gallstones

  • Cholesterol gallstones. Cholesteral gallstones often appears yellow and are spherical (round). They are mostly composed of unresolved cholesteral
  • Pigment gallstones. Pigment gallstones are mostly dark brown or black. They often form from products of blood breakdown
  • Mixed gallstones. These are the most common form, usually composed of cholesterol and pigment together

Risk factors of gallstones

  • Being female
  • Being age 40 or older
  • Being overweight or obese
  • Being sedentary
  • Having diabetes
  • Being pregnant
  • Eating a high-fat or high-cholesterol diet
  • Eating a low-fibre diet
  • Having some types of liver disease
  • Having a family history of gallstones
  • Having certain blood disorders, such as sickle cell anaemia or leukaemia
  • Losing weight very quickly
  • Taking medications that contain oestrogen, such as oral contraceptives or hormone therapy drugs

Symptoms of gallstones

  • Sudden and intense pain in the upper abdomen either just below the breastbone or underneath the ribs on the right side.
  • This can also seem to spread to the shoulder or the shoulder blade.
  • There can be associate nausea and vomiting and sometimes the pain can be associated with a fever, sweats, chills or yellowness around the eyes and the skin.

Diagnosis of gallstones

  • Abdominal ultrasound. This is the most commonly used test to look for gallstones. A handheld device is moved across your upper abdomen and uses sound waves to image the gallbladder, liver and associated structures
  • Blood tests. Blood tests are done to check that the gallstones are not causing problems beyond the gallbladder
  • Further specialised tests may be indicated and will be discussed if required.

Treatment of gallstones

Prevention of gallstones

  • Don’t skip meals. Try to stick to your usual mealtimes each day. Skipping meals or fasting can increase the risk of gallstones
  • Lose weight slowly. If you need to lose weight, go slow. Rapid weight loss can increase the risk of gallstones. Aim to lose 0.5 to 1 kilogram
    (1 to 2 pounds) a week
  • Eat more high-fibre foods. Include more fibre-rich foods in your diet, such as fruits, vegetables and whole grains
  • Maintain a healthy weight. Obesity and being overweight increase the risk of gallstones. Work to achieve a healthy weight by reducing the number of calories you eat and increasing the amount of physical activity you get. Once you achieve a healthy weight, work to maintain that weight by continuing your healthy diet and continuing to exercise.
  • Abdominal pain so intense that you canʼt sit still or find a comfortable position
  • Yellowing of your skin and the whites of your eyes (jaundice)
  • High fever with chills.
  • Gallstone pain (also known as biliary colic).  This is upper abdominal pain that occurs when gallstones block the gallbladder from emptying.  This usually happens after eating fatty/oily food and tends to last for minutes up to 2 hours
  • Inflammation of the gallbladder (also known as cholecystitis). If the gallstones blocking the gallbladder do not shift, the gallbladder can become inflamed. This causes longer lasting pain with added fever and symptoms of illness
  • Blockage of the common bile duct. Gallstones can escape the gallbladder and block the ducts that take bile to the small intestine. This can cause pain, jaundice (yellowness of the eyes and skin) and bile duct infection
  • Blockage of the pancreatic duct. The pancreatic duct is a tube that connects the pancreas to the common bile duct just as it enters the duodenum (the first part of the small intestine). Gallstones that escape the gallbladder can also block this pancreatic duct, which can cause pancreatitis (inflammation of the pancreas). Symptoms are severe, constant abdominal pain and usually require hospitalisation
  • Gallbladder cancer. People with a long history of gallstones have an increased risk of gallbladder cancer. As gallbladder cancer is very rare, the likelihood of gallbladder cancer is still very small.
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